High Fat Diets for Diet-Induced Obesity Models
A Brief Review of the Scientific Literature- October 2008
by Angela M. Gajda, M.S., Senior Scientist, Research Diets, Inc.
Genetic and environmental factors play a role in the development 
of obesity, and diet is one of the main environmental factors that 
500 contributes to this disease. Human studies have shown that 
increased fat intake is associated with body weight gain which can 
lead to obesity and other related metabolic diseases. Animal rodent  Body Weight (g)
250 DR models are therefore useful tools for studying obesity as they will 
readily gain weight when fed high-fat diets